N-Heterocyclic carbenes
نویسنده
چکیده
The N-heterocyclic carbenes (NHC) now hold a preferredligand status in organic and organometallic chemistry. Their role in catalysis continues to grow. When the editorial staff at the Beilstein Journal of Organic Chemistry contacted me to act as a guest editor for the thematic series “N-Heterocyclic carbenes”, I was more than happy to accept what appeared to me to be a simple and exciting endeavor. Indeed, the job was made simple as the number of research groups focusing on this topic continues to grow and today the literature is flooded with one use or another of these fascinating, stabilizing ligands.
منابع مشابه
Asymmetric catalysis with N-heterocyclic carbenes as non-covalent chiral templates.
N-heterocyclic carbenes are a class of persistent carbenes stabilized by adjacent heteroatoms that are part of a heterocycle. They play a central role in multiple enzymatic biosynthetic reactions that involve thiamine diphosphate. Inspired by this biocatalysis machinery, N-heterocyclic carbenes have emerged as one of the most versatile classes of organocatalysts for organic reactions. However, ...
متن کاملSynthesis of phosphorus esters by transesterification mediated by N-heterocyclic carbenes (NHCs).
The versatile nucleophilic organic catalysts N-heterocyclic carbenes (NHCs) have been shown to effectively mediate the transesterification of phosphorus esters under mild conditions; user-friendly imidazolium salts can also be employed as pre-catalysts.
متن کاملCerberus-type N-heterocyclic carbenes: synthesis and study of the first tritopic carbenes with D(3h)-symmetry.
The synthesis and characterization of tris(N-heterocyclic carbene)s with D(3h)-symmetry is reported; these tritopic molecules feature three independent carbene moieties that are geometrically isolated to prevent chelation.
متن کاملZwitterionic borane adducts of N-heterocyclic carbenes from mesomeric betaines of uracil.
We prepared a series of imidazolium-substituted uracil-anions which are members of the class of cross-conjugated heterocyclic mesomeric betaines. They are in tautomeric equilibrium with their N-heterocyclic carbenes, uracil-6-yl-imidazol-2-ylidenes. These carbenes can be trapped by reaction with sulfur, selenium, as well as by triethylborane and triphenylborane, respectively. The latter trappin...
متن کاملReaction of N-heterocyclic carbenes with chalcones leading to the synthesis of deoxy-Breslow intermediates in their oxidized form.
The synthesis of deoxy-Breslow intermediates in their oxidized form has been developed via the reaction of N-heterocyclic carbenes (NHCs) with chalcones. Moreover, the initial tetrahedral adduct formed from the 1,4-addition of NHCs to chalcones is also isolated.
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